According to a report released in the October 1 issue of the journal SLEEP.

This combination may decrease the threshold for safe driving considerably, as suggested by the steering deviation data and an increase in off-street collisions following sleep restriction and alcohol ingestion in this study.. Alcohol and rest restriction can affect little men’s alertness and traveling performance Combining low-dose alcohol with moderate sleep restriction can have a significant adverse effect on young men’s subjective alertness and efficiency behind the wheel, according to a report released in the October 1 issue of the journal SLEEP. The study, authored by Andrew Vakulin, of the Adelaide Institute for Sleep Health at Repatriation General Hospital in Australia, focused on 21 healthy young men, aged 18-30 years, who all had regular sleep patterns no sleep disorders.Full Calendar year 2013 GAAP Financial Outcomes Alexion reported GAAP net gain of $252.9 million, or $1.27 per talk about, in 2013 in comparison to 2012 GAAP net gain of $254.8 million, or $1.28 per share. Full year 2013 GAAP results were influenced by $153.0 million, or $0.77 per share, related to noncash tax expense associated with centralizing certain business operations, impairment of intangible property, expenses from permit agreements, and an intellectual residence settlement. Full year 2012 GAAP results included an increase of $27.1 million, or $0.13 per share, related to the net effect of an intellectual house settlement and an impairment of an intangible asset.