Alkermes announces preliminary results from ALKS 33 Stage 2 study in alcohol dependence Alkermes.
today announced preliminary results from a phase 2 clinical study of ALKS 33, among Alkermes‘ proprietary applicants for the treating reward disorders and other central nervous system disorders. The 12-week study was made to assess the security and efficacy of daily oral administration of three different dosage levels of ALKS 33 compared to placebo in 400 alcohol dependent patients. Furthermore to even more traditional measurements of efficacy, the analysis also tested a fresh efficacy endpoint untested in a clinical trial previously, that was a measurement of full abstinence from weighty drinking.The medical profile of patients with IHD has transformed also, with patients frequently being older and suffering from more diseases than previously. We were therefore amazed to discover that gated SPECT remains the very best predictor of long term cardiac events in patients with IHD. Furthermore, although remaining ventricular ejection fraction is additionally used in clinical practice to predict individual outcome, this research revealed that the degree of harm to the center muscle-as proven in the SPECT images-is a better prognosticator of how patients will fare. This ability to identify individuals at risk for future cardiac occasions, such as heart attacks, has substantial appeal as the early initiation of preventive therapies may alter the span of the disease, noted the experts.