That may trigger autism.

As a result, this could affect how the brain is organized and wired. Moreover, we discovered that an elevated level of PGE2 can increase expression of Wnt-regulated genes – Ctnnb1, Ptgs2, Ccnd1, and Mmp9. ‘Interestingly, each one of these genes have already been previously implicated in a variety of autism studies.’ Autism is considered to be the primary disorder of brain advancement with symptoms which range from mild to serious and including repetitive behaviour, deficits in social conversation, and impaired vocabulary. It is four times more frequent in boys than in women and the incidence continues to rise.Serra, M.D., Diane Poster, M.D., Andreas D. Kistler, M.D., Fabienne Krauer, B.S., Shagun Raina, M.S., James Adolescent, Ph.D., Katharina M. Rentsch, Ph.D., Katharina S. Spanaus, M.D., Oliver Senn, M.D., M.P.H., Paulus Kristanto, Ph.D., Hans Scheffel, M.D., Dominik Weishaupt, M.D., and Rudolf P.D.: Kidney and Sirolimus Growth in Autosomal Dominant Polycystic Kidney Disease Autosomal dominant polycystic kidney disease is the most frequent hereditary kidney disease and the cause of end-stage renal disease in 7 to 10 percent of all patients undergoing dialysis.